Dr Travis Brown on LinkedIn: #pathology #lactoseintolerance #lactasepersistence #medicine… (2024)

Dr Travis Brown

General Pathologist at Clinpath Pathology

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Episode 62: Lactose intolerance | Udderly unbearableOver two-thirds of the world’s population lose the ability to metabolise during their lifetime (the majority during childhood). We know today that lactose intolerance, or lactase persistence, has a strong genetic predisposition. Almost 100% of Asians, 70% of African-Americans, East Indians, US Hispanics and approximately 50% of Spanish and French have very low levels of lactase in adulthood (what we would call lactose intolerant). Alternatively, the majority of Caucasians can tolerate lactose into adulthood.Testing for lactose intolerance/lactase persistence can be done either via chemical or genetic testing. Each has their advantages and disadvantages but is important for any doctor or patient to know about. This is the story of Lactose intolerance/Lactase persistenceOur special guests include:Dr Michael Page is a Chemical Pathologist and Chief Executive Officer at Clinipath in Western AustraliaDr Melanie Galea is a Genetic Pathology specialist and Director of genetics at Douglass Hanly Moir Pathology in SydneyWebsite: https://lnkd.in/g9WXh9M3#pathology #lactoseintolerance #lactasepersistence #medicine #medicaleducation

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Fascinating insights on lactose intolerance. The genetic aspect is truly compelling. Thanks for sharing Dr Travis Brown

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    Episode 61: Pelvic pain & endometriosis | More than the black spotsPelvic pain is a difficult and challenging medical condition for both patients and doctors. It can be debilitating for women that can begin as a teenager or a young adult and progress for years impacting every facet of their lives. Similiarly, pelvic pain can be challenging for symptom to assess and manage for doctors as there are a multitude of causes that range from simple and straight forward to complex and chronic diseases such as endometriosis. In this episode we discuss pelvic pain and endometriosis with two guests who are leaders in diagnosis, treatment and management. This is the story of pelvic pain and endometriosisOur special guests: Dr Alecia Macrow who is a General Practitioner, owner of Thrive Family Practice, and one of 22 clinics around Australia that received government funding to assist patients with pelvic pain and endometriosis.A/Professor Susan Evans who is a Gynaecologist, Surgeon and Pain management physician in Adelaide. A/Prof Evans is Executive Chair of the Pelvic Pain Foundation of Australia (https://lnkd.in/g-A9S-cw) and CEO of Alyra Biotech which is a biopharmaceutical company developing intrauterine products for pain relief.This Medical Life podcast is available on all podcasting services & SpotifyWebsite link: https://lnkd.in/gS9shGeQ#podcast #podcasting #endometriosis #surgery #medicine #pathology #pathologists

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    Episode 60: Vitamin B6 | Vib6raniumVitamin B6 is a common additive in supplements, energy drinks and breakfast cereals. In rare circ*mstances, it can reach levels toxic levels and cause neurological symptoms the mimic neurodegenerative diseaseThis year newsGP reported a case where a GP took magnesium supplements for muscle cramps and over the course of a few years resulted in vitamin B6 toxicity that caused peripheral neuropathy and difficulty walkingFortunately, vitamin B6 toxicity is rare but it is an important condition for doctors to be aware of particularly in the setting of patients presenting with peripheral neuropathyThis is the story of vitamin B6Our special guest is Dr David Kanowski who is a senior chemical pathologist at Sullivan Nicolaides PathologyThis Medical Life podcast is available on all podcasting services & SpotifyLink: https://lnkd.in/gejvFa2r#pathology #pathologists #science #medicine #vitamins #podcast #podcasts #Imstilldoinglinkedhashtags #why #idontknow

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    Episode 59: Scleroderma | Arboreal integumentScleroderma is a disease characterized by the hardening and tightening of the skin and connective tissues. The first medical description can be traced back to the 1750s. Our understanding has evolved over the centuries but the pathogenesis remains largely unknown. The disease has several forms including diffuse and localised. Symptoms include skin discoloration and tightness to more severe complications like organ dysfunction. Fortunately we have several different treatment options available for patients that can assist them in managing this disease. This is the story of Scleroderma. Our special guest is Dr. Daman Langguth, a renowned clinical and laboratory immunologist with deep expertise in autoimmune diseases. Dr. Langguth discusses the importance of recognising scleroderma’s symptoms, the critical nature of early diagnosis, and the latest advancements in treatment. Image: Rembrandts ‘Portrait of a scholar’ shows a man with a pinched nose, tight mouth, pale face, puffy hands and a swollen right thumb leading some to raise of the question of whether he had scleroderma.This Medical Life podcast is available on all podcasting services and Spotify. Help support us at https://lnkd.in/gTp--46F#medicine #science #pathology #pathologist #autoimmune #scleroderma #stilldoinghashtags #noideawhy #guessIlikewastingmytime #ifyoureadingthissodoyou

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    Episode 58: Rickettsia | Ticking the Spotted Fever boxIn 1901, the state of Montana organised for scientists and doctors to investigate a mysterious illness from the Bitterroot Valley called ‘Black measles’ and ‘Black typhus’. People of all ages were affected but predominantly those who worked in the brush and were exposed to tick bites. The investigators called it ‘tick fever’ and this particular strain had a mortality rate over eighty percent.Today this disease is known as Rocky Mountain spotted fever. In Australia, it is sometimes called ‘spotted fever’ or ‘Queensland tick typhus’. It is caused by an obligate intracellular bacterial micro-organism (needs a cell to survive). This organism is very difficult to culture and can be even more difficult to diagnose but surprisingly easy to treat. Rickettsial disease is an under-recognised infection and important in the differential diagnosis of any patients presenting with fevers, headaches and rash.This is the story of RickettsiaOur special guest:Professor Stephen Graves who is a medical microbiology and founder of the Australian Rickettsial Reference Laboratory (ARRL). He specialises is infectious diseases transmitted by ectoparasites such as ticks, lice, fleas and mites.This Medical Life podcast is available on all podcasting services and Spotify#pathology #medicine #surgery #podcast #podcasts #rickettsia #microbiology #whydoIbotherwithlinkedinhashtagsIhavenoideaiftheyevenwork #futility #probably

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  • Dr Travis Brown

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    Episode 57: Fantastic Faeces and where to find pathogens | MetapanelA new stool sample test is available in Australia that tests 175 organism/targets/pathogens and it's called MetapanelIn the 19th century, Dr Robert Koch help to shaped modern microbiology and medicine when he identified the causative agents for anthrax and tuberculosis. Since that time, the number of infectious microorganisms that we know of that cause illness and diseases has increased exponentially. Thanks to modern day techniques, laboratories can test for these agents directly or indirectly and get an answer often within hours.Microbiology is on the verge of a new era where one test can detect hundreds of potential pathogens and antimicrobial resistance genes in a single stool sample. The new test is called Metapanel and it includes 175 gene targets using metagenomics (shotgun gene sequencing) and is able to detect bacteria, viruses, helminths, protozoa, fungi, microsporidia. This information is collated and reported by a pathologist and advice given as to what is the implications of the result. This test is ideally suited for patients with chronic diarrhoea, inflammatory bowel disease and/or inflammatory bowel syndrome.This is the story of advanced faeces testing and Metapanel.Our special guest is Dr Michael Wehrhahn is the Director of Molecular Biology and Infectious serology at Douglass Hanly Moir Pathology. Michael has a Master in Public Health, is an Infectious Disease Specialist as well as a Microbiologist and Adjunct Senior Lecturer at the University of Notre Dame.Continuous Professional Development hours available for our General Practitioners listenersThis Medical Life podcast is available on all podcasting services & SpotifyWebsite link: https://lnkd.in/gjypgvhz#podcast #podcasting #pathology #pathologists #medicine #inflammatoryboweldisease #chronicdiarrhea #science

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  • Dr Travis Brown

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    Episode 56: Iron studies | The Iron-Clad ChroniclesThis week on This Medical Life podcast, we delve into the critical topic of iron studies, with a special focus on iron deficiency, under the expert guidance of returning guest, Professor Ken Sikaris.Iron deficiency’s prevalence is influenced by factors such as age, sex, and ethnicity, noting that women, especially those of childbearing age and pregnant women, are at higher risk. Prof Sikaris addresses the challenges and misconceptions surrounding iron studies, particularly the reliability of various tests like serum iron, transferrin saturation, and ferritin. While ferritin is the most reliable marker for total body iron stores, it can be influenced by factors like inflammation.Through this episode, we provide This Medical Life provides a comprehensive exploration of iron deficiency, combining historical context, clinical insights, and practical advice, all aimed at improving understanding and management of this prevalent health issue.Our special guest is Professor Ken Sikaris (Ken Melbourne Pathology) who is a chemical pathologist and Director of Chemical Pathology at Melbourne Pathology. This Medical Life podcast is available on all podcasting services and Spotify. Website link: https://lnkd.in/gX6tGWuV#podcast #podcasting #pathology #pathologist #science #medicine #irondeficiency #ironstudies #irondeficiencyanemia #irondeficiencyanaemia

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  • Dr Travis Brown

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    Episode 54: Chronic Traumatic Encephalopathy (CTE) | Advocacy & prevention, part 2 (CPD hours)In part 1, we learned that CTE is a neurodegenerative disease caused by repetitive cumulative brain injury. Patients suffer from debilitating mental health symptoms and may even have suicidal thoughts or actions. Unfortunately, there is no treatment for this disease and it can only be official diagnosed at autopsy (after death). The only successful strategy to combat this illness is prevention.Unfortunately, this is an ongoing challenge as there is a lot we don’t know about CTE but some features are clear. The largest risk factor for CTE is the duration of time participating in contact sport. In order to prevent CTE, the aim is to reduce life time exposure to repeated head impacts (either direct or indirect ie. significant acceleration and deceleration injuries). We also delve into grass-roots education aimed at informing school-aged children about concussion and brain health.Our special guests include:Amanda Green – wife to National Rugby League legend player and coach Paul Green who played 162 first-grade games and represented Australia. At the end of 2022, Paul was found unresponsive in his home. Paul’s brain was donated to the Australian Sporting Brain Bank for examination where he was diagnosed with CTE. Paul was 49 years old.Associate Professor Michael Buckland – Head of the Neuropathology department at Royal Prince Alfred Hospital, founder and director of the Australian Sports Brain Bank (ASBB), co-director of the Multiple Sclerosis Australian Brain Bank, and Head of the Molecular Neuropathology Program at the Brain & Mind Centre.Doctor Stephanie Adams – Honorary Fellow in Sports & Brain Health at the University of Edinburgh. She is founder and director of ConcussEd which is an education program for school-aged children to learn about brain health. She is a retired rugby and equestrian athlete.This Medical Life podcast is available on all podcasting services and Spotify. This Medical Life podcast website: https://lnkd.in/ekaNsu-d#medicine #medicaleducation #doctors #pathology #pathologist #pathologists #podcast #podcasts #podcasting Help support this podcast at: https://lnkd.in/gTp--46F

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  • Dr Travis Brown

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    Episode 53: Chronic Traumatic Encephalopathy (CTE) | The disease, part 1 (CPD hours)In 2005, Dr Bennet Omalu would publish a report in the United States on the autopsy brain findings of a former professional footballer from the NFL. His conclusion was the former athlete suffered from Chronic Traumatic Encephalopathy (CTE); a disease caused by repeated brain injuries most likely due to sport. The response was swift and severe claiming that the findings were incorrect, the conclusions erroneous, and a retraction of this report was demanded.Surprisingly, this was not the first time medical literature has noted the link between sport, repeated head injuries and brain damage. The first publication was written in 1928 by Dr Harrison Martland who was the Chief Medical Examiner of Essex County in New Jersey. Harrison performed hundreds of autopsies on people with head injuries including boxers. He noted twenty-three examples of boxers with permanent brain damage that he called ‘punch drunk’. Other researchers found this was not limited to boxing but other contact sports such as football. Later, this condition became known as Dementia pugilistica.This disease has surged into the spotlight in the last decade due to a number of high-profile athletes diagnosed with CTE. Unfortunately, both professional and amateur athletes are at risk. This condition also greatly impacts the family and friends of those who suffer from it. These two episodes are designed to explain what we know, what we don’t, and what can be done about this debilitating condition.This is the story of CTE, part 1 brought to you in conjunction with The Royal College of Pathologists of Australasia (RCPA).* Please note: General Practitioners in Australia will be able to claim 2.25 CPD hours after listening to this episode and part 2. Full details and registration on ourGP CPD Pointspage.Our special guests:Renee Tuck– sister of Shane Tuck who was a professional footballer in the Australian Football League (AFL) playing 173 games and a brief career as a boxer. Later in Shane’s career, he suffered from mental health issues and in July 2020 took his own life. Shane was diagnosed with a severe form of CTE. He was only 38 years old.Associate Professor Michael Buckland– Head of the Neuropathology department at Royal Prince Alfred Hospital, founder and director of the Australian Sports Brain Bank (ASBB), co-director of the Multiple Sclerosis Australian Brain Bank, and Head of the Molecular Neuropathology Program at the Brain & Mind Centre.Associate Professor Linda Iles– Head of the Forensic Pathology Services at the Victorian Institute of Forensic Medicine (VIFM). VIFM is in partnership with the ASBB to send brain specimens for further examination/analysis for suspected CTE or other neurodegenerative diseases.This Medical Life podcast is available on all podcasting services and Spotify. Help support us athttps://lnkd.in/gTp--46FWebsite link: https://lnkd.in/g8kTXQxq

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  • Dr Travis Brown

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    This Medical Life podcast is back...and now with CPD hoursWe begin this year with one of the most important topics for General Practitioners in 2024: what are the Continuous Professional Development requirements for doctors and how have they changed?Our special guest is Rachel White who is the Managing Director for theAustralian Medical CPD Standards (AMcpdS)who has over twenty years supporting high quality medical education. We discuss the yearly requirements for doctors, component breakdown and what has changed.This is the story of CPD for 2024.We are also thrilled to announce that 6 of our genetics episodes from our catalogue (‘genetics module’) have been approved for official CPD hours for General Practitioners. These episodes are:Episode 10: Familial hypercholesterolaemia (FH)Episode 15: Lynch syndromeEpisode 21: Marfan syndromeEpisode 30&Episode 31: BrCa (Breast Cancer genes)Episode 40: Carrier screeninghttps://lnkd.in/g-jZ4XaeRegister with us on our website(https://lnkd.in/guYEWbzi) and we will send you a certificate to lodge with your CPD home to claim 5.75 hours when you have listened to them.We have also registered with https://lnkd.in/gTp--46Fwhere you can subscribe for free to get a short update when new episodes are published, or make a one-off or regular contribution to help fund this work, which is being created without any outside funding support.With your support, we hope to accredit more of our episodes in the future. Thank you for listening to, and sharing, our podcast. All episodes available on all podcasting services and Spotify.#medicine #medical #medicaleducation #pathology #pathologist #pathologists #continuouseducation #doctor #doctors #podcast #podcasts #podcasting

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